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Cake day: January 13th, 2024

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  • medgremlin@midwest.socialtoScience Memes@mander.xyzClever, clever
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    8 days ago

    Generative AI like ChatGPT is absolutely useless for anything besides maybe making summaries. Humans use language as a default method of communication, and if you are trying to produce academic work, the onus is on you to learn how to use language effectively. These heaps of algorithms and marketing exclusively hallucinate and plagiarize, both of which are absolutely unacceptable in academia (and should be unacceptable in society at large, in my opinion.)


  • medgremlin@midwest.socialtoScience Memes@mander.xyzClever, clever
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    9 days ago

    Tell me you haven’t reviewed classmates’ papers without telling me you haven’t reviewed classmates’ papers.

    Some of the papers I’ve read from my classmates make me wonder how they got out of high school, let alone into university or (!!) medical school. There are a lot of people who cannot write decently to save their lives that are still somehow in academia.






  • I just finished my surgery rotation for medical school and I saw so many colonoscopies. I have seen the inside of dozens of people’s colons and this is a pretty good explanation for what’s going on. I could also tell which patients ate a lot of fruit or seeds because there would still be some residual seeds in there after the clean-out prep.

    Pro tip: if you are going in for a colonoscopy, ask for the pill form of the prep. Most insurances cover it, it works better, and you don’t have to drink the gallon of disgusting fluid.

    Also! Colonoscopies are very important! They are the single best tool for detecting and preventing colon cancer. During the scope, if they find any polyps, they get removed and sent for evaluation to see if they are cancerous, pre-cancerous, or benign, and the polyps are basically the seeds of colon cancer. It is recommended to get your first colonoscopy at age 45, unless you have a family history of colon cancer, in which case you would get your first one 10 years younger than the age the family member was diagnosed, or age 45, whichever is younger.

    There are the home tests like the cologuard, but that has a 45% false positive rate, and they’re only good for 3 years while a colonoscopy is good for 10 years(*) if it comes back normal, so the cologuard ends up being more expensive in the long run. It also only detects the later, more advanced polyps that are more likely to be closer to being cancer, and if it comes back positive, you have to get a colonoscopy anyways. A lot of the false positives come from the fact that it tests for DNA associated with cancer mutations and for microscopic blood in the stool, and they don’t tell you if it’s positive because of the DNA or the blood, and you can have microscopic amounts of blood in your stool for tons of reasons.

    TL;DR: Colonoscopies are very important, and MUCH better than the home test. Talk to your primary care provider about when you should start screening, and if you’re over 45, go get scheduled for one now. Colon cancer is a horrible disease, and it’s actually quite preventable and easy to catch in the early stages, if you get your colonoscopies on the recommended schedule.

    *Addendum: If your colonoscopy detects certain kinds of polyps, or more than a certain number of polyps, you might be on a shorter interval for surveillance scopes to make sure they catch anything before it becomes cancer, and that interval can be anywhere from 3 to 7 years depending on what they found. Also, if you have a family history of colon or rectal cancer, you’ll be on a 5 year schedule because you’re higher risk.




  • While that gene therapy does exist, it is not the same as what is being done here. The offspring of these mosquitos will have this same modified gene. The offspring of the recipients of the Sickle Cell gene therapy will not have the modified gene. We have the ability to alter a single human for their lifespan, but we do not have the ability to alter a human in such a way that their offspring will carry the same modification.





  • CRISPR is profoundly difficult and expensive, and gets more difficult and expensive the more chromosomes are at play. Modifying mosquitos is much easier, and with the short generations (days or weeks instead of decades for humans) it’s much easier to get the genetic changes to stick and observe their efficacy. We might get around to modifying humans someday, but it will likely be centuries before it is available for anything besides fixing lethal anomalies (and even then, it’ll be a long time until that becomes consistently successful).




  • I use Proton when I’m on my university’s campus because they switched to using EDUroam for the campus wifi. I used to be a Sys Admin at a different university a while back, and from what I know, EDUroam allows the IT department to monitor basically all of the traffic over the network. I don’t know exactly how deep that stuff goes, but if I was doing anything personal or sensitive like banking or whatever, I’d flip on the VPN on my personal computer. I also don’t have any personal accounts logged in on the school issued laptop because they have it loaded with institutional spyware. Once I graduate, I’ll blank the drive and reinstall the OS to have a decent Lenovo laptop on hand as a spare.

    Edit to add: I use Proton because it was the least shady service that I could get for a reasonable price as a student. It is also helpful for finding textbooks. :)